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Thursday, 31. Jan. 2013 |
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15:15 – 16:15 |
Abstract : I
will review a rapidly developing field of electronic biological molecular
imaging and sequencing using local probes. I will describe a search for a
working and scalable alternatives to the conventional chemical methods of DNA
sequencing that are based on electronic/ionic signatures. Success of this
effort would revolutionize the field of sequencing. The approach based on a
single molecule imaging and spectroscopy with unprecedented resolution,
achieved by Scanning Tunneling Spectroscopy (STS) and nanopore electronics
could enable this breakthrough. We use the data from our group and others to
illustrate possibilities of electronic sequencing of freeze dried deposits on
graphene. Thus fingerprints of DNA-graphene hybrid structures may provide an
alternative route to DNA sequencing using STS.